Bishop of Heraclea, Upper Egypt. Arrested in the final persecution of the Church, he was condemned to the mines and had one eye gouged out and one leg rendered lame, as was the custom of branding prisoners. Released by the decree of Emperor Constantine the Great, Potamon took part in the Council of Nicaea but was then severely persecuted by the Arians of Egypt, who were outraged by his unequivocal support for the equally persecuted St. Athanasius of Alexandria. He died from the indignities and cruelties inflicted upon him by the heretics. Some accounts state that the Arians beat him to death.
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